UALCAN is a comprehensive, user-friendly, and interactive web resource for analyzing cancer OMICS data. It is built on PERL-CGI with high quality graphics using javascript and CSS. UALCAN is designed to, a) provide easy access to publicly available cancer OMICS data (TCGA and MET500), b) allow users to identify biomarkers or to perform in silico validation of potential genes of interest, c) provide graphs and plots depicting gene expression and patient survival information based on gene expression, d) evaluate gene expression in molecular subtypes of breast and prostate cancer, e) evaluate epigenetic regulation of gene expression by promoter methylation and correlate with gene expression, f) perform pan-cancer gene expression analysis, and g) Provide additional information about the selected genes/targets by linking to HPRD, GeneCards, Pubmed, TargetScan, The human protein atlas, DRUGBANK, Open Targets and the GTEx. These resources allow researchers to gather valuable information and data about the genes/targets of interest.